diff --git a/static/src/app/screens/product_screen/control_buttons/control_buttons.xml b/static/src/app/screens/product_screen/control_buttons/control_buttons.xml
index d7e7830..e356f44 100644
--- a/static/src/app/screens/product_screen/control_buttons/control_buttons.xml
+++ b/static/src/app/screens/product_screen/control_buttons/control_buttons.xml
@@ -9,5 +9,9 @@
         <xpath expr="//button[contains(@t-on-click.stop, 'clickTransferCourse') or contains(@t-on-click, 'clickTransferCourse') or contains(., 'Transfer course')]" position="replace">
             <!-- Hidden Transfer Course button -->
         </xpath>
+        <!-- Disable Bill button if there are unsent changes -->
+        <xpath expr="//button[@t-on-click='clickPrintBill']" position="attributes">
+            <attribute name="t-att-disabled">!pos.getOrder()?.getOrderlines()?.length or pos.getOrderChanges().nbrOfChanges</attribute>
+        </xpath>
     </t>
 </templates>